01 - Preheat oven to 375°F. Lightly grease a 9x13 inch baking dish with cooking spray or butter.
02 - Pat chicken breasts dry with paper towels. Season both sides evenly with salt and black pepper. Arrange seasoned chicken in the prepared baking dish in a single layer.
03 - In a medium bowl, combine mayonnaise (or Greek yogurt), 1/2 cup Parmesan cheese, garlic powder, onion powder, paprika, and dried parsley. Mix until fully incorporated and smooth.
04 - Spread the sauce mixture evenly over the tops of each chicken breast, ensuring complete coverage. Use the back of a spoon to distribute sauce uniformly.
05 - Sprinkle remaining 1/4 cup Parmesan cheese over the sauce-coated chicken. Add breadcrumbs if using for extra crunch.
06 - Bake uncovered for 25 to 30 minutes until chicken reaches an internal temperature of 165°F and the topping is golden brown and bubbly.
07 - Remove from oven and let chicken rest for 5 minutes before serving. Garnish with additional fresh parsley if desired.